首页> Journal of Alzheimer's disease : JAD> Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.

Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.

导出 OA

翻译打印收藏纠错

第一作者： Matthew G,Engel

第一单位： Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.;Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA.

作者： Matthew G,Engel ^[1] ; Sushma,Narayan ^[1] ; Min-Hui,Cui ^[2] ; Craig A,Branch ^[2] ; Xusheng,Zhang ^[3] ; Samuel E,Gandy ^[4] ; Michelle,Ehrlich ^[4] ; Derek M,Huffman ^[5]

作者单位： Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.;Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA. ^[1] Department of Radiology, Albert Einstein College of Medicine, Bronx, NY, USA. ^[2] Computational Genomics Core, Albert Einstein College of Medicine, Bronx, NY, USA. ^[3] Department of Neurology and the Mount Sinai Center for Cognitive Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Psychiatry and the Mount Sinai Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[4] Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.;Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, USA.;Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA. ^[5]

关键词 Alzheimer's disease IGF-1 LR3-IGF-1 amyloid intranasal