Structural and mechanism-based engineering of sulfotransferase CHST15 for the efficient synthesis of chondroitin sulfate E.

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第一作者： Zhonghua,Wang

第一单位： School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, China.

作者： Zhonghua,Wang ^[1] ; Wei,Song ^[1] ; Wanqing,Wei ^[2] ; Hejia,Qi ^[2] ; Weiwei,Meng ^[2] ; Jia,Liu ^[2] ; Xiaomin,Li ^[2] ; Cong,Gao ^[2] ; Liming,Liu ^[2] ; Guipeng,Hu ^[1] ; Yiwen,Zhou ^[1] ; Jing,Wu ^[1]

作者单位： School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, China. ^[1] School of Biotechnology, Jiangnan University School of Biotechnology, Wuxi, China.;Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China. ^[2]

关键词 chondroitin sulfate A chondroitin sulfate E enzyme engineering whole‐cell catalys

主题词软骨素硫酸盐类(Chondroitin Sulfates);磺基转移酶类(Sulfotransferases);蛋白质工程(Protein Engineering);细菌蛋白质类(Bacterial Proteins);大肠杆菌(Escherichia coli)

DOI 10.1128/aem.01573-24

PMID 39629983

发布时间 2025-02-04

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准确一般字义偏差语意偏离译文作用小提交