换一批
第一作者：
Julie,Le Borgne
第一单位：
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.
作者：
Julie,Le Borgne [1]
;
Lissette,Gomez [2]
;
Sami,Heikkinen [3]
;
Najaf,Amin [4]
;
Shahzad,Ahmad [5]
;
Seung Hoan,Choi [6]
;
Joshua,Bis [7]
;
Benjamin,Grenier-Boley [1]
;
Omar Garcia,Rodriguez [2]
;
Luca,Kleineidam [8]
;
Juan,Young [2]
;
Kumar Parijat,Tripathi [9]
;
Lily,Wang [10]
;
Achintya,Varma [2]
;
Rafael,Campos-Martin [9]
;
Sven,van der Lee [11]
;
Vincent,Damotte [1]
;
Itziar,de Rojas [12]
;
Sagnik,Palmal [1]
;
EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE [13]
;
Richard,Lipton [14]
;
Eric,Reiman [15]
;
Ann,McKee [16]
;
Philip,De Jager [17]
;
William,Bush [18]
;
Scott,Small [19]
;
Allan,Levey [20]
;
Andrew,Saykin [21]
;
Tatiana,Foroud [22]
;
Marilyn,Albert [23]
;
Bradley,Hyman [24]
;
Ronald,Petersen [25]
;
Steven,Younkin [26]
;
Mary,Sano [27]
;
Thomas,Wisniewski [28]
;
Robert,Vassar [29]
;
Julie,Schneider [30]
;
Victor,Henderson [31]
;
Erik,Roberson [32]
;
Charles,DeCarli [33]
;
Frank,LaFerla [34]
;
James,Brewer [35]
;
Russell,Swerdlow [36]
;
Linda,Van Eldik [2]
;
Kara,Hamilton-Nelson [37]
;
Henry,Paulson [38]
;
Adam,Naj [39]
;
Oscar,Lopez [40]
;
Helena,Chui [41]
;
Paul,Crane [42]
;
Thomas,Grabowski [43]
;
Walter,Kukull [44]
;
Sanjay,Asthana [45]
;
Suzanne,Craft [46]
;
Stephen,Strittmatter [47]
;
Carlos,Cruchaga [48]
;
James,Leverenz [49]
;
Alison,Goate [50]
;
M Ilyas,Kamboh [51]
;
Peter St,George-Hyslop [38]
;
Otto,Valladares [38]
;
Amanda,Kuzma [38]
;
Laura,Cantwell [52]
;
Matthias,Riemenschneider [53]
;
John,Morris [2]
;
Susan,Slifer [54]
;
Carolina,Dalmasso [55]
;
Atahualpa,Castillo [56]
;
Fahri,Küçükali [57]
;
Oliver,Peters [58]
;
Anja,Schneider [59]
;
Martin,Dichgans [60]
;
Dan,Rujescu [61]
;
Norbert,Scherbaum [62]
;
Jürgen,Deckert [63]
;
Steffi,Riedel-Heller [64]
;
Lucrezia,Hausner [65]
;
Laura,Molina-Porcel [66]
;
Emrah,Düzel [67]
;
Timo,Grimmer [68]
;
Jens,Wiltfang [69]
;
Stefanie,Heilmann-Heimbach [70]
;
Susanne,Moebus [71]
;
Thomas,Tegos [72]
;
Nikolaos,Scarmeas [73]
;
Oriol,Dols-Icardo [74]
;
Fermin,Moreno [75]
;
Jordi,Pérez-Tur [76]
;
María J,Bullido [77]
;
Pau,Pastor [78]
;
Raquel,Sánchez-Valle [79]
;
Victoria,Álvarez [12]
;
Mercè,Boada [80]
;
Pablo,García-González [80]
;
Raquel,Puerta [81]
;
Pablo,Mir [82]
;
Luis M,Real [83]
;
Gerard,Piñol-Ripoll [84]
;
Jose María,García-Alberca [85]
;
Jose Luís,Royo [86]
;
Eloy,Rodriguez-Rodriguez [87]
;
Hilkka,Soininen [88]
;
Alexandre,de Mendonça [89]
;
Shima,Mehrabian [89]
;
Latchezar,Traykov [90]
;
Jakub,Hort [90]
;
Martin,Vyhnalek [91]
;
Jesper Qvist,Thomassen [92]
;
Yolande A L,Pijnenburg [93]
;
Henne,Holstege [94]
;
John,van Swieten [95]
;
Inez,Ramakers [95]
;
Frans,Verhey [92]
;
Philip,Scheltens [96]
;
Caroline,Graff [97]
;
Goran,Papenberg [98]
;
Vilmantas,Giedraitis [99]
;
Anne,Boland [99]
;
Jean-François,Deleuze [100]
;
Gael,Nicolas [101]
;
Carole,Dufouil [102]
;
Florence,Pasquier [103]
;
Olivier,Hanon [104]
;
Stéphanie,Debette [105]
;
Edna,Grünblatt [106]
;
Julius,Popp [107]
;
Roberta,Ghidoni [108]
;
Daniela,Galimberti [109]
;
Beatrice,Arosio [110]
;
Patrizia,Mecocci [111]
;
Vincenzo,Solfrizzi [112]
;
Lucilla,Parnetti [113]
;
Alessio,Squassina [114]
;
Lucio,Tremolizzo [115]
;
Barbara,Borroni [116]
;
Benedetta,Nacmias [117]
;
Marco,Spallazzi [118]
;
Davide,Seripa [119]
;
Innocenzo,Rainero [120]
;
Antonio,Daniele [121]
;
Paola,Bossù [122]
;
Carlo,Masullo [123]
;
Giacomina,Rossi [124]
;
Frank,Jessen [80]
;
Victoria,Fernandez [125]
;
Patrick Gavin,Kehoe [126]
;
Ruth,Frikke-Schmidt [127]
;
Magda,Tsolaki [128]
;
Pascual,Sánchez-Juan [56]
;
Kristel,Sleegers [129]
;
Martin,Ingelsson [130]
;
Jonathan,Haines [131]
;
Lindsay,Farrer [132]
;
Richard,Mayeux [133]
;
Li-San,Wang [55]
;
Rebecca,Sims [6]
;
Anita,DeStefano [38]
;
Gerard D,Schellenberg [134]
;
Sudha,Seshadri [1]
;
Philippe,Amouyel [135]
;
Julie,Williams [92]
;
Wiesje,van der Flier [136]
;
Alfredo,Ramirez [137]
;
Margaret,Pericak-Vance [138]
;
Ole A,Andreassen [139]
;
Cornelia,Van Duijn [3]
;
Mikko,Hiltunen [12]
;
Agustín,Ruiz [140]
;
Josée,Dupuis [141]
;
Eden,Martin [1]
;
Jean-Charles,Lambert [2]
;
Brian,Kunkle [142]
;
Céline,Bellenguez
作者单位：
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.
[1]
The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
[2]
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
[3]
Nuffield Department of Population Health Oxford University, Oxford, UK.
[4]
Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
[5]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
[6]
Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
[7]
Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, University of Bonn, Bonn, Germany.;German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
[8]
Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.
[9]
Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
[10]
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.
[11]
Research Center and Memory Clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.;CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
[12]
Department of Neurology, Albert Einstein College of Medicine, New York, NY, USA.
[13]
Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.;Arizona Alzheimer's Consortium, Phoenix, AZ, USA.;Banner Alzheimer's Institute, Phoenix, AZ, USA.;Department of Psychiatry, University of Arizona, Phoenix, AZ, USA.
[14]
Department of Neurology, Boston University, Boston, MA, USA.;Department of Pathology, Boston University, Boston, MA, USA.
[15]
Program in Translational Neuro-Psychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.;Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
[16]
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.
[17]
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.;Department of Neurology, Columbia University, New York, NY, USA.
[18]
Department of Neurology, Emory University, Atlanta, GA, USA.
[19]
Department of Radiology, Indiana University, Indianapolis, IN, USA.;Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
[20]
Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
[21]
Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
[22]
Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
[23]
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
[24]
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
[25]
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA.
[26]
Center for Cognitive Neurology and Departments of Neurology, New York University, School of Medicine, New York, NY, USA.;Department of Psychiatry, New York University, New York, NY, USA.
[27]
Cognitive Neurology and Alzheimer's Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
[28]
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.;Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.;Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, IL, USA.
[29]
Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.;Department of Neurology & Neurological Sciences, Stanford University, Stanford, CA, USA.
[30]
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
[31]
Department of Neurology, University of California Davis, Sacramento, CA, USA.
[32]
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA.
[33]
Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
[34]
University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.
[35]
Sanders-Brown Center on Aging and University of Kentucky Alzheimer's Disease Research Center, Department of Neuroscience, University of Kentucky, Lexington, KY, USA.
[36]
Michigan Alzheimer's Disease Center, Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
[37]
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
[38]
University of Pittsburgh Alzheimer's Disease Research Center, Pittsburgh, PA, USA.
[39]
Department of Neurology, University of Southern California, Los Angeles, CA, USA.
[40]
Department of Medicine, University of Washington, Seattle, WA, USA.
[41]
Department of Neurology, University of Washington, Seattle, WA, USA.;Department of Radiology, University of Washington, Seattle, WA, USA.
[42]
Department of Epidemiology, University of Washington, Seattle, WA, USA.
[43]
Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.;Department of Medicine, University of Wisconsin, Madison, WI, USA.;Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA.
[44]
Gerontology and Geriatric Medicine Center on Diabetes, Obesity, and Metabolism, Wake Forest School of Medicine, Winston-Salem, NC, USA.
[45]
Program in Cellular Neuroscience, Neurodegeneration & Repair, Yale University, New Haven, CT, USA.
[46]
Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA.
[47]
Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA.
[48]
Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA.
[49]
University of Pittsburgh Alzheimer's Disease Research Center, Pittsburgh, PA, USA.;Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
[50]
Department of Medicine (Neurology), Tanz Centre for Research in Neurodegenerative Disease, Temerty Faculty of Medicine, University of Toronto, and University Health Network, Toronto, ON, USA.;Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University Irving Medical Center, 630 West 168th Street, New York, NY, 10032, USA.
[51]
Klinik für Psychiatrie und Psychotherapie, Saarbrücken, Germany.
[52]
Department of Neurology, Washington University, St. Louis, MO, USA.;Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.
[53]
Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.;Estudios en Neurociencias y Sistemas Complejos (ENyS) CONICET-HEC-UNAJ, Buenos Aires, Argentina.
[54]
Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Wales, UK.
[55]
Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.;Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
[56]
German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.;Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Hindenburgdamm 30, 12203, Berlin, Germany.
[57]
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.;Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
[58]
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.;German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.;Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
[59]
Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany.
[60]
Department of Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Germany, Medical Faculty, Duisburg, Germany.
[61]
Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germany.
[62]
Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, 04103, Leipzig, Germany.
[63]
Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
[64]
Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, Fundació Recerca Clinic Barcelona- Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), and University of Barcelona, Barcelona, Spain.;Neurological Tissue Bank-Biobank, Hospital Clinic-FRCB-IDIBAPS, Barcelona, Spain.
[65]
German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.;Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany.
[66]
Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany.
[67]
Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.;German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.;Medical Science Department, iBiMED, Aveiro, Portugal.
[68]
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
[69]
Institute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany.
[70]
1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece.
[71]
Taub Institute for Research in Alzheimer's Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York, NY, USA.;1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
[72]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Sant Pau Memory Unit, Institut de Recerca Sant Pau (IR Sant Pau), Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
[73]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain.;Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain.
[74]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain.;Unidad Mixta de Neurologia Genètica, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
[75]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain.;Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.;Universidad Autónoma de Madrid, Madrid, Spain.
[76]
Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain.;Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.
[77]
Alzheimer's Disease and Other Cognitive Disorders Unit, Service of Neurology, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.
[78]
Laboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain.;Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
[79]
Research Center and Memory Clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
[80]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
[81]
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.;Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología, Facultad de Medicina, Universidad de Málaga, Málaga, Spain.
[82]
Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.;Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain.
[83]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain.
[84]
Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología, Facultad de Medicina, Universidad de Málaga, Málaga, Spain.
[85]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
[86]
Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland.
[87]
Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
[88]
Clinic of Neurology, UH "Alexandrovska", Medical University-Sofia, Sofia, Bulgaria.
[89]
Memory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Praha, Czech Republic.
[90]
Department of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
[91]
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
[92]
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands.
[93]
Department of Neurology, Erasmus MC, Rotterdam, The Netherlands.
[94]
Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, The Netherlands.
[95]
Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, 171 64, Stockholm, Sweden.
[96]
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
[97]
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
[98]
Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France.
[99]
Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Genetics and CNRMAJ, F-76000, Rouen, France.
[100]
Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ. Bordeaux, Bordeaux, France.;CHU de Bordeaux, Pole Santé Publique, Bordeaux, France.
[101]
Univ. Lille, Inserm 1171, CHU Clinical and Research Memory Research Centre (CMRR) of Distalz, Lille, France.
[102]
Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France.
[103]
University Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France.;Department of Neurology, Bordeaux University Hospital, Bordeaux, France.
[104]
Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.;Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.;Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.
[105]
Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.;Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich, Zürich, Switzerland.;Institute for Regenerative Medicine, University of Zürich, Zurich, Switzerland.
[106]
Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, 25125, Italy.
[107]
Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy.;Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
[108]
Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy.;Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy.
[109]
Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.;Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
[110]
Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unit, University of Bari "A. Moro", Bari, Italy.
[111]
Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy.
[112]
Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy.
[113]
Neurology Unit, "San Gerardo" Hospital, Monza and University of Milano-Bicocca, Milan, Italy.
[114]
Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.;Cognitive and Behavioural Neurology, Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia, Brescia, Italy.
[115]
Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy.;IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
[116]
Department of Medicine and Surgery, Unit of Neurology, University-Hospital of Parma, Parma, Italy.
[117]
Department of Hematology and Stem Cell Transplant, Vito Fazzi Hospital, Lecce, Italy.
[118]
Department of Neuroscience "Rita Levi Montalcini", University of Torino, Torino, Italy.
[119]
Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.;Neurology Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.
[120]
Laboratory of Experimental Neuropsychobiology, IRCCS Santa Lucia Foundation, Rome, Italy.
[121]
Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
[122]
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
[123]
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.;Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.;Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
[124]
Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
[125]
Department of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.;Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
[126]
1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece.;Laboratory of Genetics, Immunology and Human Pathology, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunis, Tunisia.
[127]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII, Madrid, Spain.
[128]
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.;Krembil Brain Institute, University Health Network, Toronto, ON, Canada.;Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.
[129]
Department of Population and Quantitative Health Sciences and Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.
[130]
Department of Neurology, Boston University, Boston, MA, USA.;Department of Biostatistics, Boston University, Boston, MA, USA.;Department of Epidemiology, Boston University, Boston, MA, USA.;Department of Medicine (Biomedical Genetics), Boston University, Boston, MA, USA.;Department of Ophthalmology, Boston University, Boston, MA, USA.
[131]
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.;Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.
[132]
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
[133]
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.;Boston University and the NHLBI's Framingham Heart Study, Boston, MA, USA.;Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
[134]
Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Wales, UK.;UK Dementia Research Institute, Cardiff University, Cardiff, UK.
[135]
Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, University of Bonn, Bonn, Germany.;German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.;Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.;Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.;Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany.
[136]
The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.;Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA.
[137]
NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[138]
Nuffield Department of Population Health Oxford University, Oxford, UK.;Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
[139]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.;Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.
[140]
The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.;Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, FL, USA.;University of Miami Miller School of Medicine, Miami, FL, USA.
[141]
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France. celine.bellenguez@pasteur-lille.fr.
[142]
医学主题词
人类(Humans);阿尔茨海默病(Alzheimer Disease);全基因组关联研究(Genome-Wide Association Study);女(雌)性(Female);染色体, 人, X(Chromosomes, Human, X);男(雄)性(Male);疾病遗传易感性(Genetic Predisposition to Disease);多态性, 单核苷酸(Polymorphism, Single Nucleotide);老年人(Aged);X染色体失活(X Chromosome Inactivation);老年人, 80以上(Aged, 80 and over);病例对照研究(Case-Control Studies)
DOI
10.1038/s41380-024-02838-5
PMID
39633006
发布时间
2025-09-09
- 浏览0
Molecular psychiatry
Molecular psychiatry
2335-2346页
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