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Assessing Human Lung Pharmacokinetics Using Exhaled Breath Particles.

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第一作者： O,Holz

第一单位： Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover (Germany).;German Center for Lung Research (DZL-BREATH), Hannover (Germany).;Hannover Medical School, Department of Respiratory Medicine and Infectious Disease, Hannover (Germany).

作者： O,Holz ^[1] ; M W,Sadiq ^[2] ; C,Gress ^[3] ; N,Struß ^[4] ; S,Stomilovic ^[2] ; A,Lundqvist ^[2] ; J M,Hohlfeld ^[1]

作者单位： Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover (Germany).;German Center for Lung Research (DZL-BREATH), Hannover (Germany).;Hannover Medical School, Department of Respiratory Medicine and Infectious Disease, Hannover (Germany). ^[1] Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden. ^[2] Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover (Germany).;German Center for Lung Research (DZL-BREATH), Hannover (Germany). ^[3] Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover (Germany). ^[4]

关键词 breath analysis bronchoalveolar lavage non-invasive sampling pharmacokinetics