AIM2 promotes the progression of HNSCC via STAT1 mediated transcription and IL-17/MAPK signaling.

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第一作者： Dong,Ding

第一单位： Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China; NHC Key Laboratory of Human Disease Comparative Medicine, Institute of Laboratory Animal Science, PR China; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Chinese Academy of Medical Sciences&Peking Union Medical College, Beijing 100021, PR China; Departments of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province 230001, PR China.

作者： Dong,Ding ^[1] ; Hongfei,Liu ^[2] ; Liping,Zhang ^[3] ; Guoxin,Zhang ^[3] ; Yumin,Wei ^[3] ; Wenlong,Zhang ^[3] ; Xingjiu,Yang ^[3] ; Mengyuan,Li ^[3] ; Gaofei,Yin ^[2] ; Wei,Guo ^[2] ; Xiaohong,Chen ^[4] ; Zhigang,Huang ^[5] ; Ran,Gao ^[6]

作者单位： Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China; NHC Key Laboratory of Human Disease Comparative Medicine, Institute of Laboratory Animal Science, PR China; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Chinese Academy of Medical Sciences&Peking Union Medical College, Beijing 100021, PR China; Departments of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei, Anhui Province 230001, PR China. ^[1] Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China. ^[2] NHC Key Laboratory of Human Disease Comparative Medicine, Institute of Laboratory Animal Science, PR China; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Chinese Academy of Medical Sciences&Peking Union Medical College, Beijing 100021, PR China. ^[3] Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China. Electronic address: trchxh@163.com. ^[4] Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China. Electronic address: huangzhigang1963@163.com. ^[5] NHC Key Laboratory of Human Disease Comparative Medicine, Institute of Laboratory Animal Science, PR China; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Chinese Academy of Medical Sciences&Peking Union Medical College, Beijing 100021, PR China. Electronic address: gaoran@cnilas.org. ^[6]

关键词 AIM2 Head and neck squamous cell carcinoma IL17 MAPK pathway STAT1