Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability.

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第一作者： Masakazu,Nagamine

第一单位： Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine, Tokyo, Japan.;Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.

作者： Masakazu,Nagamine ^[1] ; Ayako,Kaitani ^[2] ; Kumi,Izawa ^[2] ; Tomoaki,Ando ^[2] ; Akihisa,Yoshikawa ^[3] ; Masahiro,Nakamura ^[4] ; Akie,Maehara ^[2] ; Risa,Yamamoto ^[2] ; Yoko,Okamoto ^[2] ; Hexing,Wang ^[1] ; Hiromichi,Yamada ^[5] ; Keiko,Maeda ^[6] ; Nobuhiro,Nakano ^[2] ; Toshiaki,Shimizu ^[5] ; Hideoki,Ogawa ^[2] ; Ko,Okumura ^[2] ; Jiro,Kitaura ^[1]

作者单位： Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine, Tokyo, Japan.;Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[1] Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[2] Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.;Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[3] Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[4] Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.;Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[5] Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.;Department of Immunological Diagnosis, Juntendo University Graduate School of Medicine, Tokyo, Japan. ^[6]

关键词 MRGPRX2 chymase degranulation histamine mast cell sensory neuron substance P vascular permeability