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A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis.

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第一作者: Sina,Bohnacker
第一单位: Department of Immunobiology, Université de Lausanne, Epalinges, Switzerland.;Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.
作者单位: Department of Immunobiology, Université de Lausanne, Epalinges, Switzerland.;Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany. [1] Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany. [2] Protein Expression and Purification Facility (PEPF), Institute of Structural Biology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany. [3] Institute for Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany.;Center for Global Health, Technical University of Munich, Munich, Germany.;German Center for Infection Research (DZIF), Munich, Germany. [4] Department of Immunobiology, Université de Lausanne, Epalinges, Switzerland. [5] Department of CryoEM Technology, Max Planck Institute of Biochemistry, Martinsried, Germany.;Cryo-Electron Microscopy Platform and Institute of Structural Biology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany. [6] Department of Medical Biochemistry and Biophysics, Division of Chemistry II, Karolinska Institutet, Stockholm, Sweden. [7] Institute of Clinical Pharmacology, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.;Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Frankfurt am Main, Germany. [8] Institute of Computational Biology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany. [9] Metabolomics and Proteomics Core, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany. [10] Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden. [11] Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany. [12] Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.;Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden. [13] Department of Medicine, Division of Rheumatology, Karolinska Institutet and Karolinska University Hospital at Solna, Stockholm, Sweden. [14] Cryo-Electron Microscopy Platform and Institute of Structural Biology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany.;Bavarian NMR-Center, Department Chemie, Technische Universität München, Garching, Germany. [15] Infektionsbiologische Abteilung, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany. [16] Center for Functional Protein Assemblies (CPA), Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany. [17]
DOI 10.1126/sciimmunol.adl1467
PMID 39642243
发布时间 2024-12-13
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Science immunology

Science immunology

2024年9卷102期

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