A neuraminidase-based inactivated influenza virus vaccine significantly reduced virus replication and pathology following homologous challenge in swine.

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第一作者： Bryan S,Kaplan

第一单位： USDA-ARS, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, USA.

作者： Bryan S,Kaplan ^[1] ; Carine K,Souza ^[2] ; J Brian,Kimble ^[1] ; Meghan Wymore,Brand ^[1] ; Tavis K,Anderson ^[1] ; Phillip C,Gauger ^[3] ; Daniel R,Perez ^[4] ; Amy L,Baker ^[5]

作者单位： USDA-ARS, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, USA. ^[1] USDA-ARS, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, USA; Dept. of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, USA. ^[2] Dept. of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, USA. ^[3] Dept. of Population Health, Poultry Diagnostic and Research Center, University of Georgia, Athens, GA, USA. ^[4] USDA-ARS, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, USA. Electronic address: amy.l.baker@usda.gov. ^[5]

关键词 Influenza Neuraminidase Swine Vaccine

主题词动物(Animals);神经氨酸酶(Neuraminidase);流感疫苗(Influenza Vaccines);猪(Swine);正黏病毒科感染(Orthomyxoviridae Infections);疫苗, 灭活(Vaccines, Inactivated);病毒复制(Virus Replication);猪疾病(Swine Diseases);抗体, 病毒(Antibodies, Viral);病毒脱落(Virus Shedding);流感病毒A型(Influenza A virus);流感病毒A型, H3N2亚型(Influenza A Virus, H3N2 Subtype)

DOI 10.1016/j.vaccine.2024.126574

PMID 39645432

发布时间 2025-01-20

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A neuraminidase-based inactivated influenza virus vaccine significantly reduced virus replication and pathology following homologous challenge in swine.

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A neuraminidase-based inactivated influenza virus vaccine significantly reduced virus replication and pathology following homologous challenge in swine.

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