Dual pH-responsive CRISPR/Cas9 ribonucleoprotein xenopeptide complexes for genome editing.

导出 LinkOut

翻译打印收藏纠错

第一作者： Xianjin,Luo

第一单位： Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität Munich, Butenandtstrasse 5-13, 81377 Munich, Germany.

作者： Xianjin,Luo ^[1] ; Janin,Germer ^[1] ; Tobias,Burghardt ^[1] ; Melina,Grau ^[1] ; Yi,Lin ^[1] ; Miriam,Höhn ^[1] ; Ulrich,Lächelt ^[2] ; Ernst,Wagner ^[3]

作者单位： Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität Munich, Butenandtstrasse 5-13, 81377 Munich, Germany. ^[1] Center for Nanoscience (CeNS), LMU Munich, 80799 Munich, Germany; Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria. ^[2] Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität Munich, Butenandtstrasse 5-13, 81377 Munich, Germany; Center for Nanoscience (CeNS), LMU Munich, 80799 Munich, Germany; CNATM - Cluster for Nucleic Acid Therapeutics Munich, Germany. Electronic address: ernst.wagner@lmu.de. ^[3]

关键词 CRISPR Cas9 Cas9/sgRNA ribonucleoprotein Genome editing Homology-directed repair Lipo-xenopeptide

主题词人类(Humans);核糖核蛋白类(Ribonucleoproteins);氢离子浓度(Hydrogen-Ion Concentration);肽类(Peptides)

DOI 10.1016/j.ejps.2024.106983

PMID 39647515

发布时间 2025-01-13

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交