Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

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第一作者： Titia Q,Ruijs

第一单位： Centre for Human Drug Research, Leiden, The Netherlands.;Leiden University Medical Centre, Leiden, The Netherlands.

作者： Titia Q,Ruijs ^[1] ; Catherine M K E,de Cuba ^[1] ; Jules A A C,Heuberger ^[2] ; John,Hutchison ^[3] ; Jane,Bold ^[3] ; Thomas S,Grønnebæk ^[3] ; Klaus G,Jensen ^[3] ; Eva,Chin ^[3] ; Jorge A,Quiroz ^[3] ; Thomas K,Petersen ^[3] ; Peter,Flagstad ^[3] ; Marieke L,de Kam ^[2] ; Michiel J,van Esdonk ^[2] ; Erica,Klaassen ^[2] ; Robert J,Doll ^[2] ; Ingrid W,Koopmans ^[1] ; Annika A,de Goede ^[2] ; Linda B S,Aulin ^[4] ; Thomas H,Pedersen ^[5] ; Geert Jan,Groeneveld ^[1]

作者单位： Centre for Human Drug Research, Leiden, The Netherlands.;Leiden University Medical Centre, Leiden, The Netherlands. ^[1] Centre for Human Drug Research, Leiden, The Netherlands. ^[2] NMD Pharma A/S, Aarhus N, Denmark. ^[3] Centre for Human Drug Research, Leiden, The Netherlands.;Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands. ^[4] NMD Pharma A/S, Aarhus N, Denmark.;Department of Biomedicine, Aarhus University, Aarhus C, Denmark. ^[5]

DOI 10.1002/cpt.3516

PMID 39651850

发布时间 2024-12-09

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Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

Clinical pharmacology and therapeutics

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Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

Clinical pharmacology and therapeutics

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Clinical pharmacology and therapeutics

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