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The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets.

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第一作者： Sara,Baroni

第一单位： Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milano, Italy.

作者： Sara,Baroni ^[1] ; Tea,Carletti ^[2] ; Manuela,Donalisio ^[3] ; Irene,Arduino ^[3] ; Irene,Cazzaniga ^[4] ; Toni,Giorgino ^[5] ; Francesca,Esposito ^[6] ; Alessia,Porta ^[1] ; Luisa,Diomede ^[1] ; Ada,De Luigi ^[1] ; Marco,Gobbi ^[1] ; David,Lembo ^[3] ; Alessandro,Marcello ^[2] ; Enzo,Tramontano ^[6] ; Mario,Milani ^[5] ; Eloise,Mastrangelo ^[4]

作者单位： Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milano, Italy. ^[1] Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy. ^[2] Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Regione Gonzole, Turin, Italy. ^[3] Dipartimento di Bioscienze, Università degli Studi di Milano, Milano, Italy.;Consiglio Nazionale delle Ricerche, Istituto di Biofisica, Milano, Italy. ^[4] Consiglio Nazionale delle Ricerche, Istituto di Biofisica, Milano, Italy. ^[5] Department of Life and Environmental Sciences, University of Cagliari, Monserrato, Italy. ^[6]

关键词 ACE2 interaction Spike protein coronaviruses dual-target compound papain-like protease