Scalable Bioreactor-based Suspension Approach to Generate Stem Cell-derived Islets From Healthy Donor-derived iPSCs.

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第一作者： Kevin,Verhoeff

第一单位： Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;Department of Surgery, University of Alberta, Edmonton, AB, Canada.

作者： Kevin,Verhoeff ^[1] ; Nerea,Cuesta-Gomez ^[2] ; Jasmine,Maghera ^[3] ; Nidheesh,Dadheech ^[2] ; Rena,Pawlick ^[2] ; Nancy,Smith ^[4] ; Doug,O'Gorman ^[5] ; Haide,Razavy ^[1] ; Braulio,Marfil-Garza ^[6] ; Lachlan G,Young ^[7] ; Aducio,Thiesen ^[8] ; Patrick E,MacDonald ^[3] ; A M James,Shapiro ^[2]

作者单位： Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;Department of Surgery, University of Alberta, Edmonton, AB, Canada. ^[1] Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;Department of Surgery, University of Alberta, Edmonton, AB, Canada.;Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada. ^[2] Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;Department of Pharmacology, University of Alberta, Edmonton, AB, Canada. ^[3] Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada.;Department of Pharmacology, University of Alberta, Edmonton, AB, Canada. ^[4] Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada. ^[5] Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.;National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico.;CHRISTUS-LatAm Hub-Excellence and Innovation Center, Monterrey, Mexico. ^[6] ProtoKinetix Inc, Dalton, OH. ^[7] Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada. ^[8]