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Evaluation of T Cell Receptor Construction Methods from scRNA-Seq Data.

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第一作者： Ruonan,Tian

第一单位： Department of Rheumatology and Immunology of the Second Affiliated Hospital, and Centre of Biomedical Systems and Informatics of Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Hangzhou 310003, China.;Future Health Laboratory, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China.

作者： Ruonan,Tian ^[1] ; Zhejian,Yu ^[2] ; Ziwei,Xue ^[1] ; Jiaxin,Wu ^[2] ; Lize,Wu ^[3] ; Shuo,Cai ^[2] ; Bing,Gao ^[2] ; Bing,He ^[4] ; Yu,Zhao ^[4] ; Jianhua,Yao ^[4] ; Linrong,Lu ^[5] ; Wanlu,Liu ^[1]

作者单位： Department of Rheumatology and Immunology of the Second Affiliated Hospital, and Centre of Biomedical Systems and Informatics of Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Hangzhou 310003, China.;Future Health Laboratory, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China. ^[1] Department of Rheumatology and Immunology of the Second Affiliated Hospital, and Centre of Biomedical Systems and Informatics of Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Hangzhou 310003, China. ^[2] Future Health Laboratory, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China.;Institute of Immunology and Department of Dermatology and Rheumatology at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. ^[3] AI Lab, Tencent, Shenzhen 518000, China. ^[4] Future Health Laboratory, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314100, China.;Institute of Immunology and Department of Dermatology and Rheumatology at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.;Shanghai Immune Therapy Institute, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai 200025, China. ^[5]

关键词 Adaptive immunity Benchmark analysis T cell receptor TCR construction scRNA-seq

医学主题词受体, 抗原, T细胞(Receptors, Antigen, T-Cell);单细胞分析(Single-Cell Analysis);人类(Humans);序列分析, RNA(Sequence Analysis, RNA);软件(Software)

DOI 10.1093/gpbjnl/qzae086

PMID 39666949

发布时间 2025-04-27

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