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Targeting RTKs/nRTKs as promising therapeutic strategies for the treatment of triple-negative breast cancer: evidence from clinical trials.

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第一作者： Kasshish,Mehta

第一单位： Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Guwahati, Assam, 781039, India.

作者： Kasshish,Mehta ^[1] ; Mangala,Hegde ^[1] ; Sosmitha,Girisa ^[1] ; Ravichandran,Vishwa ^[1] ; Mohammed S,Alqahtani ^[2] ; Mohamed,Abbas ^[3] ; Mehdi,Shakibaei ^[4] ; Gautam,Sethi ^[5] ; Ajaikumar B,Kunnumakkara ^[6]

作者单位： Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Guwahati, Assam, 781039, India. ^[1] Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, 61421, Abha, Saudi Arabia.;BioImaging Unit, Space Research Centre, Michael Atiyah Building, University of Leicester, Leicester, LE1 7RH, UK. ^[2] Electrical Engineering Department, College of Engineering, King Khalid University, 61421, Abha, Saudi Arabia. ^[3] Department of Human-Anatomy, Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Ludwig-Maximilian-University, 80336, Munich, Germany. ^[4] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117600, Singapore. phcgs@nus.edu.sg.;NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117699, Singapore. phcgs@nus.edu.sg. ^[5] Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Guwahati, Assam, 781039, India. kunnumakkara@iitg.ac.in. ^[6]

关键词 Clinical trial Genetic diversity Patient stratification Personalised medicine Triple-negative breast cancer (TNBC)Tyrosine kinase

医学主题词女(雌)性(Female);人类(Humans);临床试验(主题)(Clinical Trials as Topic);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases)

DOI 10.1186/s40779-024-00582-z

PMID 39668367

发布时间 2025-01-14

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准确一般字义偏差语意偏离译文作用小提交