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Human genetic variation reveals FCRL3 is a lymphocyte receptor for <i>Yersinia pestis</i>.

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第一作者： Rachel M,Keener

第一单位： Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA.;University Program in Genetics and Genomics, Duke University, Durham, NC, USA.

作者： Rachel M,Keener ^[1] ; Sam,Shi ^[2] ; Trisha,Dalapati ^[2] ; Liuyang,Wang ^[2] ; Nicolás M,Reinoso-Vizcaino ^[2] ; Micah A,Luftig ^[2] ; Samuel I,Miller ^[3] ; Timothy J,Wilson ^[4] ; Dennis C,Ko ^[5]

作者单位： Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA.;University Program in Genetics and Genomics, Duke University, Durham, NC, USA. ^[1] Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA. ^[2] Departments of Genome Sciences, Medicine, and Microbiology, U of Washington, Seattle, WA, USA. ^[3] Department of Microbiology, Miami University, Oxford, OH, USA. ^[4] Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA.;University Program in Genetics and Genomics, Duke University, Durham, NC, USA.;Division of Infectious Diseases, Department of Medicine, School of Medicine, Duke University, Durham, NC, USA.;Lead Contact. ^[5]

关键词 B cell Fc receptor GWAS Hi-HOST ITAM balancing selection bubonic plague human evolution lymphoblastoid cell line rs2282284

DOI 10.1101/2024.12.05.626452

PMID 39677730

发布时间 2025-09-11

基金项目

R01 AI118903/AI/NIAID NIH HHS/United States R01 CA140337/CA/NCI NIH HHS/United States

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Human genetic variation reveals FCRL3 is a lymphocyte receptor for <i>Yersinia pestis</i>.

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Human genetic variation reveals FCRL3 is a lymphocyte receptor for <i>Yersinia pestis</i>.

bioRxiv

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bioRxiv

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