Role of Non-Binding T63 Alteration in IL-18 Binding.

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第一作者： Chariya,Peeyatu

第一单位： Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.

作者： Chariya,Peeyatu ^[1] ; Napat,Prompat ^[1] ; Supayang Piyawan,Voravuthikunchai ^[2] ; Niran,Roongsawang ^[3] ; Surasak,Sangkhathat ^[4] ; Pasarat,Khongkow ^[5] ; Jirakrit,Saetang ^[6] ; Varomyalin,Tipmanee ^[7]

作者单位： Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand. ^[1] Center of Antimicrobial Biomaterial Innovation-Southeast Asia and Natural Product Research Center of Excellent, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand. ^[2] Microbial Cell Factory Research Team, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani 12120, Thailand. ^[3] Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;Translational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand. ^[4] Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;Translational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;Institute of Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand. ^[5] EZ-Mol-Design Laboratory, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;International Center of Excellence in Seafood Science and Innovation, Faculty of Agro-Industry, Prince of Songkla University, Songkhla 90112, Thailand. ^[6] Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;Institute of Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.;EZ-Mol-Design Laboratory, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand. ^[7]

关键词 interleukin-18 interleukin-18 receptor molecular dynamics simulation point mutagenesis protein conformation protein dynamics