Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post-Hemorrhagic Hydrocephalus via Multi-Omics Analysis.

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作者： Juncao,Chen ^[1] ; Lin,Wang ^[2] ; Xiangwen,Peng ^[3] ; Tingting,Cheng ^[1] ; Yihui,Yang ^[1] ; Jingzhen,Su ^[4] ; Hongmei,Zou ^[1] ; Siyao,Wang ^[1] ; Yueting,Mao ^[1] ; Lixiang,Wu ^[1] ; Xuntao,Yin ^[5] ; Minxu,Li ^[4] ; Mingwei,Zhu ^[6] ; Wei,Zhou ^[1]

作者单位： Department of Neonatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China. ^[1] Department of Radiology, Guangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, 510623, China.;Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China. ^[2] Changsha Hospital for Maternal and Child Healthcare, Changsha, 410100, China. ^[3] Department of Neonatology, Dongguan Maternal and Child Health Hospital, Dongguan, 523057, China. ^[4] Department of Radiology, Guangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, 510623, China. ^[5] Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China.;Key Laboratory of Developmental Disorders in Children, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, 545006, China. ^[6]

关键词 CSPG4 cerebrospinal fluid machine learning post‐hemorrhagic hydrocephalus proteomics and metabolomics analysis

主题词人类(Humans);动物(Animals);大鼠(Rats);脑积水(Hydrocephalus);疾病模型, 动物(Disease Models, Animal);男(雄)性(Male);女(雌)性(Female);婴儿, 新生(Infant, Newborn);蛋白质组学(Proteomics);婴儿(Infant)

DOI 10.1002/advs.202410056

PMID 39686677

发布时间 2025-02-12

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2025年12卷6期

e2410056页

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Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post-Hemorrhagic Hydrocephalus via Multi-Omics Analysis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post-Hemorrhagic Hydrocephalus via Multi-Omics Analysis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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