Hydrophobic ion pairing: lipophilicity improvement of anionic macromolecules by divalent cation mediated complex formation.

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第一作者： Sera,Lindner

第一单位： Thiomatrix Forschungs- Und Beratungs GmbH, Trientlgasse 65, 6020, Innsbruck, Austria.

作者： Sera,Lindner ^[1] ; Fabrizio,Ricci ^[1] ; René,Holm ^[2] ; Dajun,Sun ^[3] ; Nathaniel,Washburn ^[4] ; Cecilia Bohns,Michalowski ^[3] ; Giustino,Di Pretoro ^[5] ; Andreas,Bernkop-Schnürch ^[6]

作者单位： Thiomatrix Forschungs- Und Beratungs GmbH, Trientlgasse 65, 6020, Innsbruck, Austria. ^[1] Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark. ^[2] Pharmaceutical Product Development & Supply, Johnson & Johnson Innovative Medicine, Turnhoutseweg 30, B-2340, Beerse, Belgium. ^[3] Immunology Discovery, Johnson & Johnson Innovative Medicine, 301 Binney St, Cambridge, MA, 02141, USA. ^[4] Drug Product Development & Delivery, Johnson & Johnson Innovative Medicine, 347 Phoenixville Pike, Malvern, PA, 19355, USA. ^[5] Thiomatrix Forschungs- Und Beratungs GmbH, Trientlgasse 65, 6020, Innsbruck, Austria. a.bernkop@thiomatrix.com. ^[6]

关键词 Divalent cations Hydrophobic ion pairing Macromolecules Oral peptide delivery Self-emulsifying drug delivery systems

DOI 10.1007/s13346-024-01760-1

PMID 39690372

发布时间 2024-12-17

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Hydrophobic ion pairing: lipophilicity improvement of anionic macromolecules by divalent cation mediated complex formation.

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Hydrophobic ion pairing: lipophilicity improvement of anionic macromolecules by divalent cation mediated complex formation.

Drug delivery and translational research

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Drug delivery and translational research

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