换一批Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States.
第一作者：
Sally L,George
第一单位：
Paediatric Oncology Experimental Medicine Centre (POEM), The Institute of Cancer Research, London, United Kingdom.;Children and Young People's Unit, The Royal Marsden Hospital, London, United Kingdom.
作者：
Sally L,George [1]
;
Claire,Lynn [2]
;
Reda,Stankunaite [3]
;
Debbie,Hughes [4]
;
Carolin M,Sauer [5]
;
Jane,Chalker [6]
;
Saira,Waqar Ahmed [6]
;
Minou,Oostveen [6]
;
Paula Z,Proszek [4]
;
Lina,Yuan [4]
;
Ridwan,Shaikh [4]
;
Sabri,Jamal [4]
;
Ama,Brew [4]
;
Jennifer,Tall [7]
;
Tony,Rogers [7]
;
Steven C,Clifford [8]
;
Josef,Vormoor [9]
;
Janet M,Shipley [10]
;
Deborah A,Tweddle [8]
;
Chris,Jones [10]
;
Courtney,Willis [11]
;
G A Amos,Burke [12]
;
Aditi,Vedi [13]
;
Lisa,Howell [14]
;
Robert,Johnston [15]
;
Helen,Rees [16]
;
Madeleine,Adams [17]
;
Angela,Jesudason [18]
;
Milind,Ronghe [19]
;
Martin,Elliott [20]
;
Emma,Ross [21]
;
Guy,Makin [22]
;
Quentin,Campbell-Hewson [23]
;
Richard G,Grundy [24]
;
Jennifer,Turnbull [24]
;
Shaun,Wilson [25]
;
Victoria,Lee [26]
;
Juliet C,Gray [27]
;
Sara,Stoneham [28]
;
Susanne A,Gatz [29]
;
Lynley V,Marshall [1]
;
Paola,Angelini [30]
;
John,Anderson [31]
;
George D,Cresswell [32]
;
Trevor A,Graham [33]
;
Bissan,Al-Lazikani [34]
;
Isidro,Cortés-Ciriano [5]
;
Pamela,Kearns [35]
;
J Ciaran,Hutchinson [6]
;
Darren,Hargrave [36]
;
Thomas S,Jacques [31]
;
Michael,Hubank [4]
;
Andrea,Sottoriva [37]
;
Louis,Chesler [1]
作者单位：
Paediatric Oncology Experimental Medicine Centre (POEM), The Institute of Cancer Research, London, United Kingdom.;Children and Young People's Unit, The Royal Marsden Hospital, London, United Kingdom.
[1]
Paediatric Oncology Experimental Medicine Centre (POEM), The Institute of Cancer Research, London, United Kingdom.;Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
[2]
Paediatric Oncology Experimental Medicine Centre (POEM), The Institute of Cancer Research, London, United Kingdom.;Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.;Clinical Genomics, Centre for Molecular Pathology, The Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom.
[3]
Clinical Genomics, Centre for Molecular Pathology, The Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom.
[4]
European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
[5]
Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
[6]
Paediatric Oncology Experimental Medicine Centre (POEM), The Institute of Cancer Research, London, United Kingdom.
[7]
Wolfson Childhood Cancer Research Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.
[8]
Princess Máxima Center and University Medical Center, Utrecht, the Netherlands.
[9]
Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom.
[10]
Royal Aberdeen Children's Hospital, Aberdeen, United Kingdom.
[11]
Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.;Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
[12]
Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
[13]
Alder-Hey Children's Hospital, Liverpool, United Kingdom.
[14]
Royal Belfast Hospital for Sick Children, Belfast, United Kingdom.
[15]
Bristol Royal Hospital for Children, Bristol, United Kingdom.
[16]
Noah's Ark Children's Hospital for Wales, Cardiff, United Kingdom.
[17]
Royal Hospital for Sick Children, Edinburgh, United Kingdom.
[18]
Royal Hospital for Children, Glasgow, United Kingdom.
[19]
Leeds General Infirmary, Leeds, United Kingdom.
[20]
Leicester Royal Infirmary, Leicester, United Kingdom.
[21]
Royal Manchester Children's Hospital, Manchester, United Kingdom.
[22]
Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.
[23]
Queen's Medical Centre, Nottingham, United Kingdom.
[24]
John Radcliffe Hospital, Oxford, United Kingdom.
[25]
Sheffield Children's Hospital, Sheffield, United Kingdom.
[26]
Southampton General Hospital, Southampton, United Kingdom.
[27]
University College London, London, United Kingdom.
[28]
Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.;Birmingham Children's Hospital, Birmingham, United Kingdom.
[29]
Children and Young People's Unit, The Royal Marsden Hospital, London, United Kingdom.;Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom.
[30]
Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.;Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom.
[31]
Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.;St. Anna Children's Cancer Research Institute, Vienna, Austria.
[32]
Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.
[33]
Department of Genomic Medicine and the Therapeutics Discovery Division, MD Anderson Cancer Center, Houston, Texas.
[34]
Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
[35]
Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom.;Haematology and Oncology Department, Great Ormond Street Hospital, London, United Kingdom.
[36]
Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom.;Computational Biology Research Centre, Human Technopole, Milan, Italy.
[37]
医学主题词
人类(Humans);后成说, 遗传(Epigenesis, Genetic);肿瘤(Neoplasms);儿童(Child);突变(Mutation);女(雌)性(Female);男(雄)性(Male);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing)
DOI
10.1158/2159-8290.CD-24-0916
PMID
39693475
发布时间
2025-04-28
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Cancer discovery
Cancer discovery
717-732页
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