Heterogeneous Cardiac-Derived and Neural Crest-Derived Aortic Smooth Muscle Cells Exhibit Similar Transcriptional Changes After TGFβ Signaling Disruption.
第一作者:
Pengwei,Ren
第一单位:
Department of Surgery (Cardiac) (P.R., B.J., A.H., G.L., W.L., R.A., G.T.), Yale School of Medicine, New Haven, CT.
作者:
主题词
动物(Animals);神经嵴(Neural Crest);信号传导(Signal Transduction);肌细胞, 平滑肌(Myocytes, Smooth Muscle);转化生长因子β(Transforming Growth Factor beta);肌, 平滑, 血管(Muscle, Smooth, Vascular);主动脉(Aorta);马凡综合征(Marfan Syndrome);疾病模型, 动物(Disease Models, Animal);肌球蛋白重链(Myosin Heavy Chains);受体, 转化生长因子β(Receptors, Transforming Growth Factor beta);细胞谱系(Cell Lineage);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);Wnt1蛋白质(Wnt1 Protein);小鼠, 近交C57BL(Mice, Inbred C57BL);单细胞分析(Single-Cell Analysis);转录, 遗传(Transcription, Genetic);主动脉瘤(Aortic Aneurysm);基因表达谱(Gene Expression Profiling);人类(Humans);男(雄)性(Male);表型(Phenotype)
DOI
10.1161/ATVBAHA.124.321706
PMID
39697172
发布时间
2025-02-06
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