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Prognostic value of residual disease (RD) biology and gene expression changes during the neoadjuvant treatment in patients with HER2+ early breast cancer (EBC).

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第一作者: Aranzazu,Fernandez-Martinez
第一单位: Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
作者单位: Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA. [1] Okayama University, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Medical AI project, Okayama, Japan. [2] Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea. [3] Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA; University of Milan, Milan, Italy. [4] Department of Medical Oncology, Hospital Clínic de, Barcelona, Spain; Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; SOLTI Breast Cancer Cooperative Group, Barcelona, Spain; Department of Medicine, University of Barcelona, Barcelona, Spain. [5] Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Hôpital Universitaire de Bruxelles (H.U.B), Université Libre de Bruxelles (ULB), Brussels, Belgium. [6] National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA; Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania. [7] Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA. [8] Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA. [9] Integrated Biology Platform, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. [10] Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B), Institut Jules Bordet, Service d'oncologie médicale, Brussels, Belgium. [11] FTE of Novartis Healthcare Pvt. Ltd, Hyderabad, India. [12] National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA. [13] Genomics and Epigenomics Shared Resource (GESR), Georgetown University Medical Center, Washington, DC, USA. [14] Oncology Department, International Breast Cancer Center (IBCC), Pangaea Oncology, Quironsalud Group, Barcelona, Spain; IOB Madrid, Institute of Oncology, Hospital Beata Maria Ana, Madrid, Spain; Medica Scientia Innovation Research (MEDSIR), Barcelona, Spain; Universidad Europea de Madrid, Faculty of Biomedical and Health Sciences, Department of Medicine, Madrid, Spain. [15] Medical Oncology Department, Hospital Arnau de Vilanova, Valencia, Spain. [16] National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA; Lombardi Comprehensive Cancer Center, Georgetown University Medical Center and MedStar Health, Washington, DC, USA. [17] Department of Medical Oncology, Hospital Clínic de, Barcelona, Spain; Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain. [18] Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, NC, USA; Division of Hematology-Oncology, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: lisa_carey@med.unc.edu. [19]
DOI 10.1016/j.annonc.2024.12.010
PMID 39706338
发布时间 2025-01-24
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