Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(<i>2H</i>)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma.

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第一作者： Qing-Qing,Li

第一单位： National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.;R & D Center, Nanjing Sanhome Pharmaceutical Co. Ltd., Nanjing 211135, China.

作者： Qing-Qing,Li ^[1] ; Xu,Quan ^[2] ; Zi-Xuan,Wang ^[3] ; Nuo,Qiao ^[3] ; Xing-Feng,Ni ^[3] ; Xiao-Long,Jing ^[3] ; Shuang-Shuang,Zhou ^[3] ; Xin-Lei,Tian ^[2] ; Guo-Chuang,Zheng ^[2] ; Kang-Ning,Zhan ^[2] ; Yu-Jing,Xu ^[3] ; Jin,Yang ^[3] ; Yun,Zhou ^[3] ; Xiao-Ting,Liang ^[3] ; Zong-Hao,Zhao ^[3] ; Tian-Hua,Wei ^[3] ; Qian,Liu ^[3] ; Ming-Yu,Bai ^[3] ; Shan-Liang,Sun ^[3] ; Yan-Cheng,Yu ^[3] ; Peng,Cao ^[4] ; Nian-Guang,Li ^[3] ; Xiao-Meng,Zhang ^[2] ; Jian,Liu ^[3] ; Zhi-Hao,Shi ^[5]

作者单位： National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.;R & D Center, Nanjing Sanhome Pharmaceutical Co. Ltd., Nanjing 211135, China. ^[1] R & D Center, Nanjing Sanhome Pharmaceutical Co. Ltd., Nanjing 211135, China. ^[2] National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. ^[3] Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China. ^[4] Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, China. ^[5]