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High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension.

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第一作者: Tsutomu,Shinohara
第一单位: Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA.;Now with Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Japan (T.S.).
作者单位: Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA.;Now with Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Japan (T.S.). [1] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA. [2] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Now with Department of Pediatrics, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul (Y.H.C.). [3] Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA.;Department of Genetics (Y.C.L.-Y., K.G., J.M.E.), Stanford University School of Medicine, CA. [4] Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Department of Cardiothoracic Surgery (K.O.), Stanford University School of Medicine, CA. [5] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Now with Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA (J.M.S.). [6] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Austria (D.G.). [7] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA. [8] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA.;Now with the National Defense Medical College, Saitama, Japan (S.I.). [9] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.).;Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Vera Moulton Wall Center for Pulmonary Vascular Diseases (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., M.R.), Stanford University School of Medicine, CA.;Department of Bioengineering (M.D., A.L.M.), Stanford University School of Medicine, CA. [10] Department of Pediatrics (T.S., J.-R.M., Y.H.C., J.M.S., J. Kaplan, A.C., L.W., D.G., S.T., S.I., M.D., W.Y., A.L.M., M.R.). [11] Department of Comparative Medicine (B.D.F., C.P.), Stanford University School of Medicine, CA. [12] Department of Radiology, Stanford University School of Medicine, CA (L.J.P.). [13] Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Japan (S.S.). [14] Department of Pediatrics, Mie University Graduate School of Medicine, Japan (Y.M.). [15] Stanford Cardiovascular Institute (T.S., J.-R.M., Y.H.C., K.O., J.M.S., J. Kaplan, A.C., L.W., S.T., S.I., M.D., A.L.M., J.M.E., M.R.), Stanford University School of Medicine, CA.;Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital (T.S., J.-R.M., Y.C.L.-Y., J. Kaplan, A.C., L.W., S.T., S.I., K.G., J.M.E., M.R.), Stanford University School of Medicine, CA.;Department of Genetics (Y.C.L.-Y., K.G., J.M.E.), Stanford University School of Medicine, CA. [16] Department of Oncology, Hematology and Bone Marrow Transplantation, University Medical Center Hamburg-Eppendorf, Germany (J. Körbelin). [17]
DOI 10.1161/ATVBAHA.124.321092
PMID 39723537
发布时间 2025-07-20
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Arteriosclerosis, thrombosis, and vascular biology

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