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首页> Scientific reports> Resolvin D1 combined with exercise rehabilitation alleviates neurological injury in mice with intracranial hemorrhage via the BDNF/TrkB/PI3K/AKT pathway.

Resolvin D1 combined with exercise rehabilitation alleviates neurological injury in mice with intracranial hemorrhage via the BDNF/TrkB/PI3K/AKT pathway.

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作者： Lv,Xiaoyu ^[1] ; Li,Dandan ^[2] ; Ouyang,Tianzhao ^[2] ; Zhang,Ziyou ^[3] ; Liu,Zhenlin ^[1] ; Li,Zhuang ^[2] ; Liu,Mingrui ^[1] ; He,Yusong ^[2] ; Zhong,Yangyang ^[2] ; Li,Yanjiao ^[1] ; Shi,Chun ^[4] ; Wang,Siqi ^[1] ; Li,Tong ^[1] ; Zhang,Bensi ^[5]

作者单位： School of Basic Medicine, Dali University, Dali, 671003, Yunnan, China. ^[1] School of clinical Medicine, Dali University, Dali, 671003, Yunnan, China. ^[2] School of Basic Medicine, Dali University, Dali, 671003, Yunnan, China.;School of clinical College, Dehong Vocational College, Yunnan, 678400, Dehong Prefecture, China. ^[3] College of Dental Medicine, Western University of Health Sciences, Pomona, CA, 91766-1854, USA. ^[4] School of Basic Medicine, Dali University, Dali, 671003, Yunnan, China. ben-si-zhang@163.com. ^[5]

关键词 Inflammation Intracerebral hemorrhage Mitophagy Neuronal Apoptosis RvD1 exercise rehabilitation

主题词动物(Animals);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);小鼠(Mice);信号传导(Signal Transduction);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);受体, trkB(Receptor, trkB);二十二碳六烯酸类(Docosahexaenoic Acids);男(雄)性(Male);身体条件作用, 动物(Physical Conditioning, Animal);颅内出血(Intracranial Hemorrhages);疾病模型, 动物(Disease Models, Animal);运动疗法(Exercise Therapy);小鼠, 近交C57BL(Mice, Inbred C57BL);细胞凋亡(Apoptosis)

DOI 10.1038/s41598-024-83019-w

PMID 39733073

发布时间 2025-01-04

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Scientific reports

Scientific reports

2024年14卷1期

31447页

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