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首页> FASEB journal : official publication of the Federation of American Societies for Experimental Biology> Ginsenoside Ro improves Salmonella Typhimurium-induced colitis through inhibition of the virulence factors SopB and SopE2 via the RAC1/CDC42/ARP2/3 pathway.

Ginsenoside Ro improves Salmonella Typhimurium-induced colitis through inhibition of the virulence factors SopB and SopE2 via the RAC1/CDC42/ARP2/3 pathway.

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作者： Xinhua,Cui ^[1] ; Yang,Wang ^[1] ; Ziyan,Liu ^[1] ; Meng,Zhao ^[1] ; Mingmei,Zhu ^[1] ; Wanlu,Yu ^[1] ; Baochun,Lu ^[1] ; Hongyue,Xu ^[1] ; Jiajia,Liu ^[1] ; Ning,Liao ^[1] ; Jinyang,Shi ^[1] ; Danping,Peng ^[1] ; Sijia,Niu ^[1] ; Jiayi,Shen ^[2] ; Jiazhang,Qiu ^[1] ; Lu,Yu ^[1]

作者单位： State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine Jilin University, Center of Infectious Diseases and Pathogen Biology, Department of Infectious Diseases, First Hospital of Jilin University, Changchun, China. ^[1] Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province, Gannan Normal University, Ganzhou, China. ^[2]

关键词 S. Typhimurium colitis ginsenoside Ro invasion virulence factors

主题词动物(Animals);人参皂甙类(Ginsenosides);小鼠(Mice);鼠伤寒沙门菌(Salmonella typhimurium);人类(Humans);结肠炎(Colitis);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein);毒力因子类(Virulence Factors);沙门菌感染(Salmonella Infections);细菌蛋白质类(Bacterial Proteins);信号传导(Signal Transduction);男(雄)性(Male);cdc42 GTP结合蛋白质(cdc42 GTP-Binding Protein);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1096/fj.202401712R

PMID 39734277

发布时间 2025-01-05

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FASEB journal

2024年38卷24期

e70282页

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