Plaque heterogeneity influences in-stent restenosis following drug-eluting stent implantation: Insights from patient-specific multiscale modelling.

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作者： Anna,Corti ^[1] ; Lucia,Dal Ferro ^[2] ; Ali C,Akyildiz ^[3] ; Francesco,Migliavacca ^[4] ; Sean,McGinty ^[5] ; Claudio,Chiastra ^[6]

作者单位： Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy. Electronic address: anna.corti@polimi.it. ^[1] Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, Italy; Division of Biomedical Engineering, University of Glasgow, Glasgow, UK; Glasgow Computational Engineering Centre, University of Glasgow, Glasgow, UK. ^[2] Department of Cardiology, Biomedical Engineering, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, the Netherlands; Department of Biomechanical Engineering, Delft University of Technology, Delft, the Netherlands. ^[3] Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, Italy. ^[4] Division of Biomedical Engineering, University of Glasgow, Glasgow, UK; Glasgow Computational Engineering Centre, University of Glasgow, Glasgow, UK. ^[5] PoliTo(BIO)Med Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy. ^[6]

关键词 Agent-based model (ABM)Atherosclerotic plaque Coronary artery Drug transport model Percutaneous coronary intervention