A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors.

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作者： Umberto,Cillo ^[1] ; Caterina,Lonati ^[2] ; Alessandra,Bertacco ^[1] ; Lucrezia,Magnini ^[3] ; Michele,Battistin ^[3] ; Liver NMP Consortium ^[1] ; Lara,Borsetto ^[4] ; Francesco,Dazzi ^[5] ; David,Al-Adra ^[1] ; Enrico,Gringeri ^[6] ; Maria Laura,Bacci ^[7] ; Andrea,Schlegel ^[8] ; Daniele,Dondossola

作者单位： Hepato-Biliary-Pancreatic Surgery and Liver Transplant Unit, General Surgery 2, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy. ^[1] Center for Preclinical Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20100, Milan, Italy. caterina.lonati@gmail.com. ^[2] Center for Preclinical Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20100, Milan, Italy. ^[3] School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, UK. ^[4] Division of Transplantation, Department of Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA. ^[5] Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy. ^[6] Center for Preclinical Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20100, Milan, Italy.;Transplantation Center, Digestive Disease and Surgery Institute, Department of Immunity and Inflammation, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44106, USA. ^[7] General and Liver Transplant Surgery Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20100, Milan, Italy.;Department of Pathophysiology and Transplantation, University of Milan, Via Francesco Sforza 35, 20100, Milan, Italy. ^[8]