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E3 ligase FBXW7 suppresses brown fat expansion and browning of white fat.

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作者: Jian,Yu [1] ; Xuejiang,Gu [2] ; Yingying,Guo [3] ; Mingyuan,Gao [4] ; Shimiao,Cheng [4] ; Meiyao,Meng [4] ; Xiangdi,Cui [4] ; Zhe,Zhang [4] ; Wenxiu,Guo [4] ; Dandan,Yan [3] ; Maozheng,Sheng [4] ; Linhui,Zhai [5] ; Jing,Ji [6] ; Xinhui,Ma [6] ; Yu,Li [4] ; Yuxiang,Cao [4] ; Xia,Wu [4] ; Jiejie,Zhao [7] ; Yepeng,Hu [2] ; Minjia,Tan [5] ; Yan,Lu [8] ; Lingyan,Xu [9] ; Bin,Liu [10] ; Cheng,Hu [11] ; Xinran,Ma [12]
作者单位: Joint Center for Translational Medicine, Fengxian District Central Hospital, Fengxian District, Shanghai, 201400, China.;Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.;Chongqing Key Laboratory of Precision Optics, Chongqing Institute of East China Normal University, Chongqing, 401120, China.;Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. [1] Department of Endocrine and Metabolic Diseases, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. [2] Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai, 200233, China. [3] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. [4] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. [5] Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China. [6] Ministry of Education Key Laboratory of Metabolism and Molecular Medicine, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200000, China. [7] Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai, 200233, China.;Ministry of Education Key Laboratory of Metabolism and Molecular Medicine, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200000, China. [8] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. lyxu@bio.ecnu.edu.cn.;Institute for Aging, East China Normal University, Shanghai, 200241, China. lyxu@bio.ecnu.edu.cn. [9] Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China. liubin@jou.edu.cn. [10] Joint Center for Translational Medicine, Fengxian District Central Hospital, Fengxian District, Shanghai, 201400, China. alfredhc@sjtu.edu.cn.;Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai, 200233, China. alfredhc@sjtu.edu.cn. [11] Joint Center for Translational Medicine, Fengxian District Central Hospital, Fengxian District, Shanghai, 201400, China. xrma@bio.ecnu.edu.cn.;Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. xrma@bio.ecnu.edu.cn.;Chongqing Key Laboratory of Precision Optics, Chongqing Institute of East China Normal University, Chongqing, 401120, China. xrma@bio.ecnu.edu.cn.;Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. xrma@bio.ecnu.edu.cn.;Institute for Aging, East China Normal University, Shanghai, 200241, China. xrma@bio.ecnu.edu.cn. [12]
DOI 10.1038/s44319-024-00337-w
PMID 39747664
发布时间 2025-02-13
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