首页> Journal of assisted reproduction and genetics> Novel variants of FSIP2 and SPEF2 cause varying degrees of spermatozoa damage in MMAF patients and favorable ART outcomes.

Novel variants of FSIP2 and SPEF2 cause varying degrees of spermatozoa damage in MMAF patients and favorable ART outcomes.

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第一作者： Cong-Ling,Dai

第一单位： NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, China.;Hunan Guangxiu Hi-Tech Life Technology Co., Ltd, Changsha, China.;Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of CITIC-Xiangya, Changsha, China.

作者： Cong-Ling,Dai ^[1] ; Xin-Yu,Yin ^[2] ; Zi-Yan,Peng ^[3] ; Hao,Lin ^[4] ; Pan,Zhang ^[4] ; Gang,Liu ^[5] ; Wei-Na,Li ^[6]

作者单位： NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, China.;Hunan Guangxiu Hi-Tech Life Technology Co., Ltd, Changsha, China.;Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of CITIC-Xiangya, Changsha, China. ^[1] NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, China. ^[2] Laboratory of Zebrafish Genetics, College of Life Sciences, Hunan Normal University, Changsha, China. ^[3] School of Medicine, Hunan Guangxiu Hospital, Hunan Normal University, Changsha, China. ^[4] NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, China.;Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of CITIC-Xiangya, Changsha, China. ^[5] NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, China. liweinaking@126.com.;Hunan Guangxiu Hi-Tech Life Technology Co., Ltd, Changsha, China. liweinaking@126.com.;Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of CITIC-Xiangya, Changsha, China. liweinaking@126.com. ^[6]

关键词 FSIP2 SPEF2 In vitro fertilization (IVF)Intracytoplasmic sperm injection (ICSI)Multiple morphological abnormalities of the sperm flagella (MMAF)Novel variation