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Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation.

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第一作者: Xinyu,Cui
第一单位: Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.;Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopaedic Department of Tongji Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
作者: Xinyu,Cui [1] ; Yu,Dong [2] ; Qiang,Zhan [3] ; Yixin,Huang [2] ; Qianshu,Zhu [1] ; Zihao,Zhang [1] ; Guang,Yang [1] ; Liping,Wang [1] ; Shijun,Shen [1] ; Jia,Zhao [1] ; Zhiyi,Lin [2] ; Jiatong,Sun [2] ; Zhongqu,Su [4] ; Yihan,Xiao [2] ; Chuyu,Zhang [2] ; Yuwei,Liang [2] ; Lu,Shen [2] ; Lichen,Ji [5] ; Xuguang,Zhang [6] ; Jiqing,Yin [2] ; Hong,Wang [2] ; Zhiyang,Chen [7] ; Zhenyu,Ju [8] ; Cizhong,Jiang [9] ; Rongrong,Le [10] ; Shaorong,Gao [11]
作者单位: Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.;Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopaedic Department of Tongji Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. [1] Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. [2] Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Department of Developmental & Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. [3] Shandong Key Laboratory of Animal Bioengineering and Disease Prevention, College of Animal Science and Technology, Shandong Agricultural University, Taian, 271018, China. [4] Department of Joint Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China. [5] Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, 200031, China. [6] Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Department of Developmental & Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. zhiyangchen@jnu.edu.cn. [7] Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Department of Developmental & Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. zhenyuju2016@jnu.edu.cn. [8] Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. czjiang@tongji.edu.cn.;Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopaedic Department of Tongji Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. czjiang@tongji.edu.cn. [9] Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. lerongrong@tongji.edu.cn. [10] Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. gaoshaorong@tongji.edu.cn. [11]
DOI 10.1007/s11427-024-2754-9
PMID 39754007
发布时间 2025-05-22
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Science China. Life sciences

Science China. Life sciences

2025年68卷5期

1209-1225页

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