TIG1 triggers placental senescence in preeclampsia through LMNA/p53 axis activation.

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作者： Yanxuan,Xiao ^[1] ; Maliang,Tao ^[2] ; Jiexing,He ^[3] ; Jiaqi,Li ^[3] ; Qiuyu,Huang ^[3] ; Yiqi,Yu ^[3] ; Mingze,Gao ^[3] ; Qian,Chen ^[4] ; Zhijian,Wang ^[5]

作者单位： Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; School of Nursing, Southern Medical University, Guangzhou, 510515, China. ^[1] Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. ^[2] Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. ^[3] Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: Chenqianqian430@qq.com. ^[4] Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Department of Obstetrics and Gynecology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. Electronic address: wzjnfyy@163.com. ^[5]

关键词 Cell senescence Placenta Preeclampsia Transcriptome Trophoblast