Oncogenic Functions of Alternatively Spliced <i>MDM2-ALT2</i> Isoform in Retroperitoneal Liposarcoma.

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作者： Fernanda Costas C,de Faria ^[1] ; Safiya,Khurshid ^[2] ; Patricia,Sarchet ^[1] ; Sayumi,Tahara ^[1] ; Lucia,Casadei ^[1] ; Valerie,Grignol ^[1] ; Roma,Karna ^[1] ; Sydney,Rentsch ^[1] ; Nipin,Sp ^[1] ; Joal D,Beane ^[1] ; Luciano,Mazzoccoli ^[3] ; Matias,Montes ^[2] ; Giovanni,Nigita ^[4] ; Joe T,Sharick ^[5] ; Jennifer L,Leight ^[5] ; Federica,Calore ^[6] ; Dawn S,Chandler ^[2] ; Raphael E,Pollock ^[1]

作者单位： The James Comprehensive Cancer Center, Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. ^[1] Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA. ^[2] Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Research, Columbus, OH 43210, USA. ^[3] Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA. ^[4] Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA. ^[5] The James Comprehensive Cancer Center, Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.;Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA. ^[6]

关键词 AKT DDLPS MDM2 variants MDM2-ALT2 MDM2-Full length WDLPS soft tissue sarcoma