Biopharmaceutical Characterization and Stability of Nabumetone-Cyclodextrins Complexes Prepared by Grinding.

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第一作者： David,Klarić

第一单位： Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia.

作者： David,Klarić ^[1] ; Željka,Soldin ^[1] ; Anna,Vincze ^[2] ; Rita,Szolláth ^[2] ; György Tibor,Balogh ^[2] ; Mario,Jug ^[3] ; Nives,Galić ^[1]

作者单位： Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia. ^[1] Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre u. 9., H-1092 Budapest, Hungary.;Center for Pharmacology and Drug Research & Development, Semmelweis University, Üllői u. 26. H-1092 Budapest, Hungary. ^[2] Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10 000 Zagreb, Croatia. ^[3]

关键词 chemical stability cyclodextrins degradants in vitro dissolution in vitro permeability mechanochemistry nabumetone solid-state characterization

DOI 10.3390/pharmaceutics16121493

PMID 39771473

发布时间 2025-01-08

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