Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration.

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作者： Sa,Huang ^[1] ; Yuan,Xu ^[2] ; Yingyao,Luo ^[2] ; Zhijiong,Wang ^[2] ; Fan,Li ^[2] ; Zhenmiao,Qin ^[3] ; Junfeng,Ban ^[2]

作者单位： Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, No. 280 University Town Outer Ring East Road, Guangzhou 510006, China.;College of Pharmacy, Guilin Medical University, No. 1 Zhiyuan Road, Guilin 541104, China.;Guangdong Laboratory Animals Monitoring Institute, No. 11 Fengxin Road, Guangzhou 510663, China. ^[1] Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, No. 280 University Town Outer Ring East Road, Guangzhou 510006, China.;The Innovation Team for Integrating Pharmacy with Entrepreneurship, Guangdong Pharmaceutical University, No. 280 University Town Outer Ring East Road, Guangzhou 510006, China. ^[2] Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Key Laboratory for Research and Development of Tropical Herbs, School of Pharmacy, Hainan Medical University, No. 3 Xueyuan Road, Haikou 571199, China. ^[3]

关键词 PLGA cell-penetrating peptides nanoparticles ocular drug delivery pharmacokinetic

DOI 10.3390/pharmaceutics16121496

PMID 39771476

发布时间 2025-01-08

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