Rapidly Manufactured CAR-T with Conserved Cell Stemness and Distinctive Cytokine-Secreting Profile Shows Improved Anti-Tumor Efficacy.

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作者： Shih-Ting,Tsao ^[1] ; Mingyuan,Gu ^[1] ; Qinghui,Xiong ^[1] ; Yingzhi,Deng ^[1] ; Tian,Deng ^[1] ; Chengbing,Fu ^[1] ; Zihao,Zhao ^[1] ; Haoyu,Zhang ^[1] ; Cuicui,Liu ^[2] ; Xiong,Zhong ^[3] ; Fang,Xiang ^[3] ; Fei,Huang ^[1] ; Haiying,Wang ^[1]

作者单位： Department of R&D, Shanghai HRAIN Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong, Shanghai 201210, China. ^[1] Department of Regulatory Affairs, Shanghai HRAIN Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong, Shanghai 201210, China. ^[2] Department of Medical Research, Shanghai HRAIN Biotechnology Co., Ltd., 1238 Zhangjiang Road, Pudong, Shanghai 201210, China. ^[3]

关键词 B-cell acute lymphoblastic leukemia CD19 anti-tumor efficacy of CAR-T chimeric antigen receptor T-cell cytokine-secreting profile of CAR-T rapid manufacture stemness of CAR-T

DOI 10.3390/vaccines12121348

PMID 39772010

发布时间 2025-01-08

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2024年12卷12期

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Rapidly Manufactured CAR-T with Conserved Cell Stemness and Distinctive Cytokine-Secreting Profile Shows Improved Anti-Tumor Efficacy.

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Rapidly Manufactured CAR-T with Conserved Cell Stemness and Distinctive Cytokine-Secreting Profile Shows Improved Anti-Tumor Efficacy.

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