The Pestivirus RNase E<sup>rns</sup> Tames the Interferon Response of the Respiratory Epithelium.

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作者： Guillaume,Beilleau ^[1] ; Hanspeter,Stalder ^[2] ; Lea,Almeida ^[2] ; Blandina I,Oliveira Esteves ^[2] ; Marco P,Alves ^[3] ; Matthias,Schweizer ^[2]

作者单位： Institute of Virology and Immunology, Länggass-Str. 122, CH-3001 Bern, Switzerland.;Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, CH-3001 Bern, Switzerland.;Graduate School for Cellular and Biomedical Sciences, University of Bern, CH-3012 Bern, Switzerland. ^[1] Institute of Virology and Immunology, Länggass-Str. 122, CH-3001 Bern, Switzerland.;Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, CH-3001 Bern, Switzerland. ^[2] Institute of Virology and Immunology, Länggass-Str. 122, CH-3001 Bern, Switzerland.;Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, CH-3001 Bern, Switzerland.;Multidisciplinary Center for Infectious Diseases, University of Bern, CH-3012 Bern, Switzerland. ^[3]

关键词 IFN antagonist air–liquid interface (ALI)bovine viral diarrhea virus (BVDV)glycosaminoglycan (GAG)-binding site innate immune evasion interferon type-I pestivirus respiratory epithelium viral RNase viral endonuclease