Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model.

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作者： Rui,Dang ^[1] ; Mridul,Dalmia ^[2] ; Ziyuan,Ma ^[1] ; Mengmeng,Jin ^[1] ; Kushal,Aluru ^[1] ; Vincent R,Mirabella ^[3] ; Ava V,Papetti ^[1] ; Li,Cai ^[2] ; Peng,Jiang ^[4]

作者单位： Department of Cell Biology and Neuroscience, Rutgers University, 604 Allison Road, Piscataway, NJ, 08854, USA. ^[1] Department of Biomedical Engineering, Rutgers University, 599 Taylor Rd, Piscataway, NJ, 08854, USA. ^[2] Child Health Institute of New Jersey and Department of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, 08901, USA. ^[3] Department of Cell Biology and Neuroscience, Rutgers University, 604 Allison Road, Piscataway, NJ, 08854, USA. peng.jiang@rutgers.edu. ^[4]

关键词 Astrogliogenesis Autism Brain organoid Human embryonic stem cells Human induced pluripotent stem cells Neurexin Neuroligin Neuroligin-3 R451C

DOI 10.1186/s13619-024-00219-5

PMID 39775628

发布时间 2025-01-11

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Cell regeneration (London, England)

2025年14卷1期

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Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model.

Cell regeneration (London, England)

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Cell regeneration (London, England)

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Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model.

Cell regeneration (London, England)

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Cell regeneration (London, England)

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