Drug repositioning of mesalamine via supramolecular nanoassembly for the treatment of drug-induced acute liver failure.

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第一作者： Byeongmin,Park

第一单位： KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.;Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.

作者： Byeongmin,Park ^[1] ; Eun Hye,Kim ^[2] ; Hochung,Jang ^[3] ; Yelee,Kim ^[2] ; Youngri,Ryu ^[2] ; Jiwoong,Choi ^[4] ; Dongwon,Shin ^[1] ; Myung Chul,Lee ^[4] ; Yoosoo,Yang ^[3] ; Kwangmeyung,Kim ^[5] ; Sangmin,Lee ^[6] ; Sun Hwa,Kim ^[1] ; Man Kyu,Shim ^[4]

作者单位： KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea.;Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea. ^[1] Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.;Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea. ^[2] Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.;Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea. ^[3] Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea. ^[4] College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. ^[5] College of Pharmacy, Graduate School of Pharmaceutical Sciences, Kyung Hee University, Seoul 02453, Republic of Korea. ^[6]

关键词 Acute liver injury Drug repositioning Mesalamine Prodrug Supramolecular assembly