换一批NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth.
第一作者：
Jonathan,Welti
第一单位：
The Institute of Cancer Research, London, United Kingdom.
作者：
医学主题词
男(雄)性(Male);人类(Humans);受体, 雄激素(Receptors, Androgen);非折叠蛋白质应答(Unfolded Protein Response);动物(Animals);小鼠(Mice);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);信号传导(Signal Transduction);细胞增殖(Cell Proliferation);E2F转录因子类(E2F Transcription Factors);基因表达谱(Gene Expression Profiling)
DOI
10.1158/1078-0432.CCR-24-2386
PMID
39787247
发布时间
2025-04-30
基金项目
Not known/Bone Cancer Research Trust (BCRT)
R21 CA277368/CA/NCI NIH HHS/United States
MR/W018217/1/Medical Research Council (MRC)
C309/A11566/Cancer Research UK (CRUK)
P50 CA097186/CA/NCI NIH HHS/United States
R01 CA234715/CA/NCI NIH HHS/United States
P50CA097186/National Institute of Health Sciences (NIHS)
SGCL15/Academy of Medical Sciences (The Academy of Medical Sciences)
RIA18-ST2-011/Prostate Cancer UK (ProstateUK)
WT_/Wellcome Trust/United Kingdom
Not known/CRIS Cancer Foundation (CRIS Foundation)
CRUK CRM186x/Cancer Research UK (CRUK)
R01 CA266452/CA/NCI NIH HHS/United States
219594/Z/19/Z/Wellcome Trust (WT)
Not known/Chordoma Foundation (CF)
N/A/NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research (BRC)
212969/Z/18/Z/Wellcome Trust (WT)
R50 CA274336/CA/NCI NIH HHS/United States
21CHAL01/Prostate Cancer Foundation (PCF)
TLD-PF19-006/Prostate Cancer UK (ProstateUK)
Not known/Mark Foundation For Cancer Research (The Mark Foundation for Cancer Research)
MR/M018318/1/Medical Research Council (MRC)
P01 CA163227/CA/NCI NIH HHS/United States
18YOUN25/Prostate Cancer Foundation (PCF)
R50CA274336/National Institute of Health Sciences (NIHS)
- 浏览1
Clinical cancer research
1109-1126页
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