De novo biosynthesis of mogroside V by multiplexed engineered yeasts.

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第一作者： Guanyi,Qu

第一单位： Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China; Food Laboratory of Zhongyuan, Jiangnan University, Wuxi, 214122, China.

作者： Guanyi,Qu ^[1] ; Yunfei,Song ^[2] ; Xianhao,Xu ^[3] ; Yanfeng,Liu ^[3] ; Jianghua,Li ^[3] ; Guocheng,Du ^[3] ; Long,Liu ^[3] ; Yangyang,Li ^[3] ; Xueqin,Lv ^[4]

作者单位： Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China; Food Laboratory of Zhongyuan, Jiangnan University, Wuxi, 214122, China. ^[1] Guilin Layn Natural Ingredients Corp, Guilin, 541000, China. ^[2] Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China; Jiangsu Province Basic Research Center for Synthetic Biology, Jiangnan University, Wuxi, 214122, China. ^[3] Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China; Science Center for Future Foods, Jiangnan University, Wuxi, 214122, China; Jiangsu Province Basic Research Center for Synthetic Biology, Jiangnan University, Wuxi, 214122, China. Electronic address: lvxueqin@jiangnan.edu.cn. ^[4]

关键词 CYP450 enzyme modification Compartmentalization Endoplasmic reticulum expansion Modular engineering Mogroside V de novo synthesis

主题词酿酒酵母菌(Saccharomyces cerevisiae);三萜类(Triterpenes)

DOI 10.1016/j.ymben.2025.01.002

PMID 39788182

发布时间 2025-02-23

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