首页> International journal of pharmaceutics> Genipin-crosslinked double PLL membranes overcome the strength-diffusion trade-off in cell encapsulation without compromising biocompatibility.

Genipin-crosslinked double PLL membranes overcome the strength-diffusion trade-off in cell encapsulation without compromising biocompatibility.

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第一作者： Edorta,Santos-Vizcaino

第一单位： NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV-EHU), 01006 Vitoria-Gasteiz, Spain; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029 Madrid, Spain; Bioaraba, NanoBioCel Research Group, 01006 Vitoria-Gasteiz, Spain.

作者： Edorta,Santos-Vizcaino ^[1] ; María,Virumbrales-Muñoz ^[2] ; Ainhoa,Gonzalez-Pujana ^[1] ; Gary D,Luker ^[3] ; Ignacio,Ochoa ^[4] ; Rosa Maria,Hernandez ^[5] ; Jose Luis,Pedraz ^[6]

作者单位： NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV-EHU), 01006 Vitoria-Gasteiz, Spain; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029 Madrid, Spain; Bioaraba, NanoBioCel Research Group, 01006 Vitoria-Gasteiz, Spain. ^[1] Department of Obstetrics and Gynecology, Clinical Sciences Center, 600 Highland Drive, Madison 53792, USA; School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison 53705, USA; University of Wisconsin Carbone Cancer Center, 1111 Highland Avenue, Madison 53705, USA. ^[2] Department of Radiology (Center for Molecular Imaging), University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA. ^[3] Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029 Madrid, Spain; Tissue Microenvironment Lab (TME Lab), I3A, University of Zaragoza, 50018 Zaragoza, Spain; Aragón Health Research Institute (IISAragón), 50009 Zaragoza, Spain; School of Medicine, University of Zaragoza, 50009 Zaragoza, Spain. ^[4] NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV-EHU), 01006 Vitoria-Gasteiz, Spain; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029 Madrid, Spain; Bioaraba, NanoBioCel Research Group, 01006 Vitoria-Gasteiz, Spain. Electronic address: rosa.hernandez@ehu.eus. ^[5] NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV-EHU), 01006 Vitoria-Gasteiz, Spain; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029 Madrid, Spain; Bioaraba, NanoBioCel Research Group, 01006 Vitoria-Gasteiz, Spain. Electronic address: joseluis.pedraz@ehu.eus. ^[6]

关键词 Cell encapsulation Foreign body reaction Genipin Mechanical properties Membranes Permeability