Activating the Astrocytes of the Dorsal Raphe Nucleus via Its Neural Circuits With the Medial Prefrontal Cortex Improves Depression in Mice.

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作者： Jingyu,Zhao ^[1] ; Yuang,Wang ^[1] ; Chunxiao,Tian ^[1] ; Jialiang,Wang ^[1] ; Feng,Chen ^[2] ; Xi,Dong ^[3] ; Jiayi,Luo ^[4] ; Yuxuan,Zhu ^[4] ; Aili,Liu ^[4] ; Zengguang,Ma ^[1] ; Hui,Shen ^[4]

作者单位： Laboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China. ^[1] Laboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.;Institute for Translational Neuroscience, The Second Affiliated Hospital of Nantong University, Nantong, China. ^[2] Laboratory of Neurobiology, School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China.;Institute for Translational Brain Research, Fudan University, Shanghai, China. ^[3] Laboratory of Neurobiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. ^[4]

关键词 DRN astrocyte chemogenetics depression mPFC

主题词动物(Animals);额叶前皮质(Prefrontal Cortex);星形细胞(Astrocytes);小鼠(Mice);抑郁(Depression);男(雄)性(Male);神经元(Neurons);应激, 心理学(Stress, Psychological);小鼠, 近交C57BL(Mice, Inbred C57BL);钙信号(Calcium Signaling);疾病模型, 动物(Disease Models, Animal);钙-钙调素依赖性蛋白激酶2型(Calcium-Calmodulin-Dependent Protein Kinase Type 2);神经通路(Neural Pathways);行为, 动物(Behavior, Animal)

DOI 10.1155/bn/8890705

PMID 39803364

发布时间 2025-01-14

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Behavioural neurology

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Activating the Astrocytes of the Dorsal Raphe Nucleus via Its Neural Circuits With the Medial Prefrontal Cortex Improves Depression in Mice.

Behavioural neurology

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Behavioural neurology

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Activating the Astrocytes of the Dorsal Raphe Nucleus via Its Neural Circuits With the Medial Prefrontal Cortex Improves Depression in Mice.

Behavioural neurology

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Behavioural neurology

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