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A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research.

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第一作者： Christian M,Beusch

第一单位： Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.;Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.

作者： Christian M,Beusch ^[1] ; Ken,Braesch-Andersen ^[2] ; Ulrika,Felldin ^[2] ; Pierre,Sabatier ^[3] ; Anna,Widgren ^[4] ; Jonas,Bergquist ^[4] ; Karl-Henrik,Grinnemo ^[5] ; Sergey,Rodin ^[6]

作者单位： Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.;Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA. ^[1] Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. ^[2] Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.;Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark. ^[3] Department of Chemistry - BMC, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden. ^[4] Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.;Department of Cardio-Thoracic Surgery and Anesthesiology, Uppsala University Hospital, Uppsala, Sweden. ^[5] Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. sergey.rodin@uu.se.;Department of Cardio-Thoracic Surgery and Anesthesiology, Uppsala University Hospital, Uppsala, Sweden. sergey.rodin@uu.se. ^[6]

医学主题词蛋白质组学(Proteomics);动物(Animals);小鼠(Mice);死后变化(Postmortem Changes);蛋白质组(Proteome);肝(Liver);脾(Spleen);心肌(Myocardium);尸体解剖(Autopsy);男(雄)性(Male);器官特异性(Organ Specificity);小鼠, 近交C57BL(Mice, Inbred C57BL);纵向研究(Longitudinal Studies)

DOI 10.1038/s42003-025-07515-z

PMID 39824970

发布时间 2025-05-01

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Communications biology

2025年8卷1期

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Communications biology

2025年8卷1期

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A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research.

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A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research.

Communications biology

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Communications biology

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