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mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction.

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第一作者: Seon-Yeong,Lee
第一单位: Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.;Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
作者单位: Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.;Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea. [1] Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT, USA. [2] Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. [3] Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.;Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.;Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. [4] Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.;Harvard Medical School, Boston, MA, USA. [5] Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, Hanyang University College of Medicine, Seoul, Korea. [6] College of Pharmacy, Gachon University, Incheon, Republic of Korea. [7] Divison of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. [8] Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. iammila@catholic.ac.kr.;Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea. iammila@catholic.ac.kr.;Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. iammila@catholic.ac.kr. [9]
DOI 10.1038/s12276-024-01376-y
PMID 39825104
发布时间 2025-05-01
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