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首页> International immunopharmacology> Microglia-derived exosomal ciRS-7 mediates IL-17A effect of promoting neurodegeneration via miR-7 and SNCA targets in an experimental Parkinson's disease.

Microglia-derived exosomal ciRS-7 mediates IL-17A effect of promoting neurodegeneration via miR-7 and SNCA targets in an experimental Parkinson's disease.

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作者： Fen-Fen,Xu ^[1] ; Zhan,Liu ^[1] ; Xiao-Xia,Fang ^[1] ; Bei-Bei,Cao ^[1] ; Yan,Huang ^[1] ; Yu-Ping,Peng ^[2] ; Yi-Hua,Qiu ^[3]

作者单位： Department of Physiology, School of Medicine, and Co-innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001 China. ^[1] Department of Physiology, School of Medicine, and Co-innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001 China. Electronic address: yp_peng@yeah.net. ^[2] Department of Physiology, School of Medicine, and Co-innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong 226001 China. Electronic address: yh_qiu@yeah.net. ^[3]

关键词 Exosome Interleukin-17A Microglia Neurodegeneration Parkinson’s disease ciRS-7

主题词动物(Animals);微RNAs(MicroRNAs);外泌体(Exosomes);白细胞介素17(Interleukin-17);α突触核蛋白(alpha-Synuclein);小神经胶质细胞(Microglia);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);男(雄)性(Male);细胞系(Cell Line);疾病模型, 动物(Disease Models, Animal);人类(Humans);帕金森病(Parkinson Disease)

DOI 10.1016/j.intimp.2025.114089

PMID 39832458

发布时间 2025-02-11

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