Analysis of skeletal diversity of multi-target directed ligands (MTDLs) targeting Alzheimer's disease.

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作者： Uzma,Azam ^[1] ; Muhammad Moazzam,Naseer ^[2] ; Christophe,Rochais ^[3]

作者单位： Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan. ^[1] Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan; Université de Caen Normandie, Normandie Univ., CERMN, 14000, Caen, France. Electronic address: moazzam@qau.edu.pk. ^[2] Université de Caen Normandie, Normandie Univ., CERMN, 14000, Caen, France. Electronic address: christophe.rochais@unicaen.fr. ^[3]

关键词 Alzheimer's disease Hybridization approach MTDLs Multifactorial Skeletal diversity

主题词阿尔茨海默病(Alzheimer Disease);人类(Humans);配体(Ligands);淀粉样β肽类(Amyloid beta-Peptides);分子结构(Molecular Structure);动物(Animals);tau蛋白质类(tau Proteins)

DOI 10.1016/j.ejmech.2025.117277

PMID 39848035

发布时间 2025-02-07

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