Chromosome number alterations cause apoptosis and cellular hypertrophy in induced pluripotent stem cell models of embryonic epiblast cells.

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作者： Althea Stella Anil,Martis ^[1] ; Loshini,Soundararajan ^[1] ; Pallavi,Shetty ^[1] ; Syed,Moin ^[1] ; Tejashree,Vanje ^[1] ; Yogeshwaran,Jai Sankar ^[1] ; Shagufta,Parveen ^[1]

作者单位： Manipal Institute of Regenerative Medicine, Manipal Academy of Higher Education, Manipal 576104, India. ^[1]

关键词 Abortive embryonic development Apoptosis Chromosomal aneuploidies Epiblast model Hypertrophy Micronuclei

主题词细胞凋亡(Apoptosis);胚层(Germ Layers);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);细胞分化(Cell Differentiation);肥大(Hypertrophy);非整倍性(Aneuploidy)

DOI 10.1242/bio.061814

PMID 39851179

发布时间 2025-02-05

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2025年14卷1期

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Chromosome number alterations cause apoptosis and cellular hypertrophy in induced pluripotent stem cell models of embryonic epiblast cells.

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Chromosome number alterations cause apoptosis and cellular hypertrophy in induced pluripotent stem cell models of embryonic epiblast cells.

Biology open

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Biology open

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