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首页> Biochemical and biophysical research communications> Inhibition of P2X7 receptor mitigates atrial fibrillation susceptibility in isoproterenol-induced rats.

Inhibition of P2X7 receptor mitigates atrial fibrillation susceptibility in isoproterenol-induced rats.

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作者： Yunping,Zhou ^[1] ; Tianxin,Ye ^[1] ; Fangcong,Yu ^[1] ; Zhuonan,Song ^[1] ; Longbo,Wang ^[1] ; Cui,Zhang ^[2] ; Bo,Yang ^[2] ; Jinxiu,Yang ^[3] ; Xingxiang,Wang ^[4]

作者单位： Department of Cardiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China. ^[1] Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, PR China; Cardiovascular Research Institute, Wuhan University, Wuhan, 430060, PR China; Hubei Key Laboratory of Cardiology, Wuhan, 430060, PR China. ^[2] Department of Cardiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China. Electronic address: zihuidaoren@163.com. ^[3] Department of Cardiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China. Electronic address: 1304016@zju.edu.cn. ^[4]

关键词 Atrial fibrillation CaMKII Mendelian randomization NADPH oxidase P2X7 receptor

主题词动物(Animals);受体, 嘌呤能P2X7(Receptors, Purinergic P2X7);异丙肾上腺素(Isoproterenol);心房颤动(Atrial Fibrillation);大鼠(Rats);男(雄)性(Male);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);嘌呤能P2X受体拮抗剂(Purinergic P2X Receptor Antagonists);纤维化(Fibrosis);疾病模型, 动物(Disease Models, Animal);孟德尔随机化分析(Mendelian Randomization Analysis);品红类染料(Rosaniline Dyes)

DOI 10.1016/j.bbrc.2025.151340

PMID 39855041

发布时间 2025-02-01

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Biochemical and biophysical research communications

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