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Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage.

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第一作者: Anders,Schlosser
第一单位: Department of Molecular Medicine, University of Southern Denmark, 5230 Odense, Denmark.
作者单位: Department of Molecular Medicine, University of Southern Denmark, 5230 Odense, Denmark. [1] Cancer Biology, Division of Cancer and Stem Cells, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham NG7 2UH, UK. [2] Molecular Bone Histology Laboratory, Department of Pathology, Odense University Hospital, 5000 Odense, Denmark; Molecular Bone Histology Laboratory, Research Unit of Pathology, Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark; Danish Spatial Imaging Consortium (DanSIC), University of Southern Denmark, 5230 Odense, Denmark. [3] OPEN - Open Patient Data Explorative Network, Odense University Hospital and Department of Clinical Research, University of Southern Denmark, 5000 Odense, Denmark. [4] Ophtha-Lab, Department of Ophthalmology, St. Franziskus Hospital, 48145 Münster, Germany; Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. [5] Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. [6] Department of Ophthalmology, Odense University Hospital, 5000 Odense, Denmark. [7] Department of Pathology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark; Department of Ophthalmology, Rigshospitalet-Glostrup, University of Copenhagen, 2600 Glostrup, Denmark. [8] Department of Ophthalmology, University of Heidelberg, 69047 Heidelberg, Germany. [9] Virscio, Inc., 5 Science Park, New Haven, CT 06511, USA. [10] Department of Clinical Biochemistry, Odense University Hospital, 5000 Odense, Denmark. [11] Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark. [12] Department of Molecular Medicine, University of Southern Denmark, 5230 Odense, Denmark. Electronic address: glsorensen@health.sdu.dk. [13]
DOI 10.1016/j.ymthe.2025.01.038
PMID 39863929
发布时间 2025-05-03
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Molecular therapy : the journal of the American Society of Gene Therapy

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