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FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis.

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第一作者： Amaya,Lopez-Pascual

第一单位： Hepatology Laboratory, Solid Tumors Program, CIMA, CCUN, University of Navarra, Pamplona, Spain.;Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain.

作者： Amaya,Lopez-Pascual ^[1] ; Eva,Santamaria ^[2] ; Nuria,Ardaiz ^[3] ; Iker,Uriarte ^[2] ; Tiffany,Palmer ^[4] ; Anne-Renee,Graham ^[4] ; Celia,Gomar ^[3] ; Roberto C,Barbero ^[2] ; M Ujue,Latasa ^[2] ; Maria,Arechederra ^[5] ; Jesus M,Urman ^[6] ; Carmen,Berasain ^[5] ; Antonio,Fontanellas ^[5] ; Carlos L,Del Rio ^[4] ; Maite G,Fernandez-Barrena ^[5] ; Paolo G V,Martini ^[4] ; Joshua R,Schultz ^[4] ; Pedro,Berraondo ^[7] ; Matias A,Avila ^[8]

作者单位： Hepatology Laboratory, Solid Tumors Program, CIMA, CCUN, University of Navarra, Pamplona, Spain.;Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain. ^[1] Hepatology Laboratory, Solid Tumors Program, CIMA, CCUN, University of Navarra, Pamplona, Spain.;CIBERehd, Madrid, Spain. ^[2] Immunology and Immunotherapy Program, CIMA, CCUN, University of Navarra, Pamplona, Spain. ^[3] Moderna Inc, Cambridge, MA, USA. ^[4] Hepatology Laboratory, Solid Tumors Program, CIMA, CCUN, University of Navarra, Pamplona, Spain.;Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain.;CIBERehd, Madrid, Spain. ^[5] Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain.;Department of Gastroenterology and Hepatology, Navarra University Hospital, Pamplona, Spain. ^[6] Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain. pberraondol@unav.es.;Immunology and Immunotherapy Program, CIMA, CCUN, University of Navarra, Pamplona, Spain. pberraondol@unav.es.;CIBERonc, Madrid, Spain. pberraondol@unav.es. ^[7] Hepatology Laboratory, Solid Tumors Program, CIMA, CCUN, University of Navarra, Pamplona, Spain. maavila@unav.es.;Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain. maavila@unav.es.;CIBERehd, Madrid, Spain. maavila@unav.es. ^[8]

关键词 APOA1 Acute pancreatitis Cytoprotection FGF21 Pancreatic injury mRNA therapy